• Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and visual field (VF) progression in primary open-angle...

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    Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Optic Disc Microvasculature Reduction and Visual Field Progression in Primary Open-Angle Glaucoma

    Purpose: To investigate the relationship between optic disc vessel density (ODVD) reduction and...

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  • Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect with or without visual field defect when located in...

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    Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    Consider cotton wool spots as potential triggers for (non-glaucomatous) nerve fibre bundle defects

    It may be tempting to make a glaucoma diagnosis in the presence of a nerve fibre bundle defect...

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  • Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence of patients with primary open-angle glaucoma (POAG)...

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    Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition

    Purpose: We tested the hypothesis that a questionnaire-based risk score predicts the prevalence...

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  • Not every ring scotoma is due to glaucoma

    In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring scotoma, where the retinal sensitivity is...

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    Not every ring scotoma is due to glaucoma

    Not every ring scotoma is due to glaucoma

    In advanced stages of glaucoma, patients may present with an annular scotoma, also known as ring...

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  • Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate of change in standard automated perimetry (SAP) in...

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    Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression

    Purpose: To examine the relationship between systemic arterial blood pressure (BP) and the rate...

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  • Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control than viscocanalostomy. DS required less glaucoma...

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    Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Comparison of Outcomes of Deep Sclerectomy, Canaloplasty, and Viscocanaloplasty: A Multi-Centred Study

    Prcis: Deep sclerectomy (DS) and canaloplasty provide better intraocular pressure (IOP) control...

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  • Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated clinical measurements between normal and glaucoma...

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    Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

    Purpose: A cross-sectional pilot study to compare macular oxygen saturation (sO2) and associated...

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  • Childhood Glaucoma

    SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma is a rare but severe ocular condition that can...

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    Childhood Glaucoma

    Childhood Glaucoma

    SIG Corner Editor: Hana Abouzeid Chair: Esther Hoffmann Co-chair: Zeynep Aktas Childhood glaucoma...

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  • Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing it too early can lead to postoperative hypotony and...

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    Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    Avoid premature removal of the intraluminal suture in glaucoma drainage devices to minimize the risk of hypotony

    While prolene suture removal is an effective method for reducing IOP at the slit-lamp, removing...

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  • Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional loss in glaucoma; (2) To evaluate the importance...

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    Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Biomechanics-Function in Glaucoma: Improved Visual Field Predictions from IOP-Induced Neural Strains

    Purpose: (1) To assess whether neural tissue structure and biomechanics could predict functional...

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  • Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Purpose: A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients...

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    Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom

    Purpose: A previously developed machine-learning approach with Kalman filtering technology...

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  • Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned people. This sociological concept is a result of...

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    Fatal beauty: which cosmetics are your glaucoma patients using?

    Fatal beauty: which cosmetics are your glaucoma patients using?

    Colorism refers to the difference in social treatment between light-skinned and dark-skinned...

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Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma

Experimental Paper of the Month

Pericyte dysfunction and loss of interpericyte tunneling nanotubes promote neurovascular deficits in glaucoma

Author(s): Luis Alarcon-Martinez (1,2), Yukihiro Shiga (3,2), Deborah Villafranca-Baughman )3,2), Nicolas Belforte (3,2), Heberto Quintero (3,2),...

March 31, 2022

Intraocular Pressure and Its Relation to Ocular Geometry: Results From the Gutenberg Health Study

NGP Paper

Intraocular Pressure and Its Relation to Ocular Geometry: Results From the Gutenberg Health Study

Author(s): Esther M Hoffmann (1), Fidan Aghayeva (1), Felix M Wagner (1), Achim Fiess (1), Markus Nagler (2), Thomas Münzel (3,4), Philipp S Wild...

March 30, 2022

When prescribing Latanoprost, don’t forget about potential cardiovascular side effects

Tip of the month

When prescribing Latanoprost, don’t forget about potential cardiovascular side effects

Prostaglandin analogues are advised as first line treatment for chronic open angle glaucoma by the European Glaucoma Society Guidelines for their...

February 28, 2022

The Weiss ring, a major confounding factor for measurements of peripapillary retinal nerve fiber layer thickness

Clinical paper of the month

The Weiss ring, a major confounding factor for measurements of peripapillary retinal nerve fiber layer thickness

Author(s): Min-Woo Lee (1), Min-Su Kim (2), Hwa-Young Yu (1), Kee-Sup Park (1), Young-Hoon Lee (1), Jung-Yeul Kim (3) 1 Department of...

February 28, 2022

GWAS identifies two common loci associated with pigment dispersion syndrome/pigmentary glaucoma and implicate myopia in its development

Experimental Paper of the Month

GWAS identifies two common loci associated with pigment dispersion syndrome/pigmentary glaucoma and implicate myopia in its development

Author(s): Mark J Simcoe (1), Ameet Shah (2), Baojian Fan (3), Hélène Choquet (4), Nicole Weisschuh (5), Naushin H Waseem (6), Chen Jiang (4),...

February 28, 2022

Neuroprotection SIG

SIG Corner

Neuroprotection SIG

SIG Corner Editor: Hana Abouzeid Chair: Maria Francesca Cordeiro Co-chair: Miriam Kolko SIG neuroprotection keeps an eye on new initiatives within...

February 21, 2022

Unilateral ocular hypertension: have a look at the corneal endothelium

Tip of the month

Unilateral ocular hypertension: have a look at the corneal endothelium

Unilateral ocular hypertension or glaucoma is often associated with secondary causes that should be explored to ascertain the visual prognosis and...

January 31, 2022

Diagnostic assessment of glaucoma and non-glaucomatous optic neuropathies via optical texture analysis of the retinal nerve fibre layer

Clinical paper of the month

Diagnostic assessment of glaucoma and non-glaucomatous optic neuropathies via optical texture analysis of the retinal nerve fibre layer

Author(s): Christopher Kai Shun Leung (1,2,3,4), Alexander Ka Ngai Lam (5), Robert Neal Weinreb (6), David F Garway-Heath (7), Marco Yu (8), Philip...

January 31, 2022

Phase 1b Randomized Controlled Study of Short Course Topical Recombinant Human Nerve Growth Factor (rhNGF) for Neuroenhancement in Glaucoma: Safety, Tolerability, and Efficacy Measure Outcomes

Experimental Paper of the Month

Phase 1b Randomized Controlled Study of Short Course Topical Recombinant Human Nerve Growth Factor (rhNGF) for Neuroenhancement in Glaucoma: Safety, Tolerability, and Efficacy Measure Outcomes

Author(s): Gala Beykin (1), Laurel Stell (1), Muhammad Sohail Halim (1), Mariana Nuñez (1), Lilia Popova (1), Bac T Nguyen (1), Sylvia L Groth (1),...

January 31, 2022

Mind the depth – forward displacement of the lens-iris diaphragm and myopic shift after ophthalmic surgery is suggestive of aqueous misdirection

Tip of the month

Mind the depth – forward displacement of the lens-iris diaphragm and myopic shift after ophthalmic surgery is suggestive of aqueous misdirection

Aqueous misdirection is a serious condition with potentially higher prevalence than expected. Predominantly observed after ocular surgery,...

December 31, 2021

Attitudes towards polygenic risk testing in individuals with glaucoma

Clinical paper of the month

Attitudes towards polygenic risk testing in individuals with glaucoma

Author(s): Georgina L Hollitt (1), Owen M Siggs (2), Bronwyn Ridge (2), Miriam C Keane (2), David A Mackey (3), Stuart MacGregor (4), Alex W Hewitt...

December 31, 2021

Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies

Experimental Paper of the Month

Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies

Author(s): Benjamin R Thomson (1,2), Pan Liu (1,2), Tuncer Onay (1), Jing Du (1,2), Stuart W Tompson (3), Sol Misener (1,2), Raj R Purohit (1,2),...

December 31, 2021

Virtual Reality-Based and Conventional Visual Field Examination Comparison in Healthy and Glaucoma Patients

NGP Paper

Virtual Reality-Based and Conventional Visual Field Examination Comparison in Healthy and Glaucoma Patients

Author(s): Jan Stapelfeldt (1), Serife Seda Kucur (1), Nina Huber (1), René Höhn (2), Raphael Sznitman (1) 1 ARTORG Center for Biomedical...

December 30, 2021

Exfoliation (pseudoexfoliation) syndrome (with or without glaucoma) is associated with clinically significant non-vascular systemic diseases

Tip of the month

Exfoliation (pseudoexfoliation) syndrome (with or without glaucoma) is associated with clinically significant non-vascular systemic diseases

The association of systemic vascular dysfunction and vascular diseases with exfoliation syndrome have been extensively studied in the last decades....

December 01, 2021

Association Between Visual Field Damage and Gait Dysfunction in Patients With Glaucoma

Clinical paper of the month

Association Between Visual Field Damage and Gait Dysfunction in Patients With Glaucoma

Author(s): Jian-Yu E (1,2), Aleksandra Mihailovic (1), Catalina Garzon (1), Jennifer A Schrack (2,3), Tianjing Li (4), Sheila K West (1), Laura N...

November 30, 2021

GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans

Experimental Paper of the Month

GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans

Author(s): K Saidas Nair (# 1), Chitrangda Srivastava (# 2), Robert V Brown (# 2), Swanand Koli (3), Hélène Choquet (4), Hong Soon Kang (2),...

November 30, 2021

Unplanned Return to the Operating Room After Trabeculectomy

Clinical paper of the month

Unplanned Return to the Operating Room After Trabeculectomy

Author(s): Nur Cardakli (1), David S Friedman (2), Michael V Boland (3) 1 Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins...

November 30, 2021

Exfoliation SIG

SIG Corner

Exfoliation SIG

The goal of this SIG is to increase ophthalmologists’ knowledge on XFS and XFG, and to support the optimal clinical care in XFG in Europe. 1....

November 01, 2021

Consider trabeculectomy as initial treatment for newly diagnosed advanced primary open angle glaucoma (POAG)

Tip of the month

Consider trabeculectomy as initial treatment for newly diagnosed advanced primary open angle glaucoma (POAG)

IOP control is of uttermost importance in advanced glaucoma to prevent blindness. The EGS guidelines recommend IOP in the low teens, e.g. 10-12mmHg...

October 31, 2021

In vivo imaging of the Schlemm's Canal and the response to Selective laser trabeculoplasty

Clinical paper of the month

In vivo imaging of the Schlemm's Canal and the response to Selective laser trabeculoplasty

Author(s): Toshit Varshney (1), Kishan Azmira (1), Shikha Gupta (1), Karthikeyan Mahalingam (1), Abhishek Singh (1), Dewang Angmo (1), Viney Gupta...

October 31, 2021

Preservation of vision after CaMKII-mediated protection of retinal ganglion cells

Experimental Paper of the Month

Preservation of vision after CaMKII-mediated protection of retinal ganglion cells

Author(s): 1 Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. 2 Department of Neuroscience, Yale...

October 31, 2021

Take a look at the deviation maps when assessing structural change in glaucoma

Tip of the month

Take a look at the deviation maps when assessing structural change in glaucoma

The structural analysis of the thickness of peripapillary retinal nerve fiber layer (pRNFL) and the inner layers of the posterior pole with optical...

September 30, 2021

Long-Term Outcomes of Selective Laser Trabeculoplasty for Open-Angle Glaucoma in the Caribbean

Clinical paper of the month

Long-Term Outcomes of Selective Laser Trabeculoplasty for Open-Angle Glaucoma in the Caribbean

Author(s): Tony Realini (1), Hazel Shillingford-Ricketts (2), Darra Burt (3), Goundappa K Balasubramani (4) 1 West Virginia University Eye...

September 30, 2021

Agonist of growth hormone-releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury

Experimental Paper of the Month

Agonist of growth hormone-releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury

Author(s): Ling-Ping Cen (1), Tsz Kin Ng (1,2,3), Jia-Jian Liang (1), Ciyan Xu (1), Xi Zhuang (1), Yu-Fen Liu (1,2), Shao-Lang Chen (1), Yanxuan Xu...

September 30, 2021

The glaucoma intensive treatment study: interim results from an ongoing longitudinal randomized clinical trial

NGP Paper

The glaucoma intensive treatment study: interim results from an ongoing longitudinal randomized clinical trial

Author(s): Boel Bengtsson (1), Christina Lindén (2), Anders Heijl (1), Sabina Andersson-Geimer (1), Johan Aspberg (1), Gauti Jóhannesson (2,3) 1...

September 30, 2021